Quality standards, including physical, chemical, and microbiological tests and criteria are important parts of the safety and efficacy of ingredients. Bonerge is aiming to offer premium-quality NAD ingredients with potent healthy values to the world.

1. BongeLov Management System

All of our products are developed and operated under our BongeLov Management System. We are proud to hold and maintain a full set of the world-class manufacturing certifications including cGMP, GMP+, FSSC22000, HACCP, ISO22000, Halal, Kosher etc, our process allows Bonerge to continue to meet the highest standards for purity, traceability and transparency that’s backed by strict controls, monitoring and tracking to provide our customers with products they trust.

2.  Analytical Procedure Life Cycle Management

With professional analytical scientists and advanced equipments, top quality and consistency among batches are the golden promises to our customers from Bonerge.

The identity test, purity test, impurity test and assay test that usually applied in the pharmaceutical industry and guided by USP requirements, is at the center of Bonerge's quality research.

3. Authoritative and credible Reference Standard(RS) for assay analysis 

A trusted RS is like an impartial judge. Reference substances are of great importance for a test method.  Bonerge always source every RS globally, and choose the authoritative and credible Reference Standard for assay analysis .

4.  Top quality botanical source for eco-friendly and cost-efficiently manufacturing

 We are making efforts to manufacture eco-friendly and cost-efficiently to make our healthy ingredients more affordable to consumers. We work with the raw material growers closely to source high quality material that can be traced through every step.  Our facility equipped with two continuous countercurrent extraction lines, and each line is available in capacities of up to hundreds tons/day raw material, enable us to produce at super largre scale and achive the best quality and cost.

As you age, the inevitable decline of NAD leads to a decrease in energy production and cellular repair. This results in energy loss, mental fatigue, the appearance of wrinkles, and a higher frequency of getting sick. However, you can make up for these deficiencies through NAD supplementation. NAD can help to：

1.  Increased Cellular Energy Levels
By supplementing with NAD, the production of cellular energy can be increased by enhancing ATP levels, which potentially improves metabolism and alleviates fatigue[1]. Research on individuals with chronic fatigue syndrome has evaluated the safety and effectiveness of NAD supplementation in relation to fatigue, quality of life, and sleep quality. The general consensus is that NAD supplementation has a positive impact on quality of life and improves health parameters such as anxiety levels, energy levels, and the immune system response.[2]

2. Improved Cellular Repair Capability
A study explored the role of NAD supplementation in DNA repair. The researchers discovered that supplementation reduced the accumulation of endogenous DNA damage and enhanced the DNA repair capacity. Ultimately, NAD supplementation may have a positive effect on DNA repair in the context of aging and in neurodegenerative diseases like Alzheimer's disease. [3]

3. Enhanced Cellular Signaling and Communication
Cellular communication is crucial for overall health, well-being, and longevity. If cells cannot promptly transmit messages to each other, aging will progress more rapidly. Since NAD functions as an assistant, its task is to ensure that things occur quickly and efficiently. Restoring NAD to its youthful levels means that your body can quickly complete its daily tasks. In this way, it restores the cell-signaling function and reduces stress. [3]

Reference:

[1]: Mehmel M, Jovanović N, Spitz U. Nicotinamide Riboside-The Current State of Research and Therapeutic Uses. Nutrients. 2020 May 31;12(6):1616.  

[2]: Gindri IM, Ferrari G, et al. Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review. Am J Physiol Endocrinol Metab. 2024 Apr 1;326(4):E417-E427.

[3]: Wilk A, Hayat F, Cunningham R, et al. Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity. Sci Rep. 2020 Jan 20;10(1):651.